Bio Calculator

10 essential tools for molecular biology students and researchers

All Tools

Protein Stats
Protein

Calculate amino acid composition and statistical analysis of protein sequences. Groups residues by chemical properties.

DNA Molecular Weight
DNA

Compute molecular weight for DNA sequences as single- or double-stranded, linear or circular molecules. Supports IUPAC degenerate bases.

DNA Stats
DNA

Calculate residue counts, dinucleotide frequencies, GC content, and grouped totals (purines vs pyrimidines) for DNA sequences.

Protein Molecular Weight
Protein

Calculate the molecular weight of protein sequences including fusion tags (FLAG, HA, His6, GST, MBP) and extinction coefficient at 280nm.

PCR Primer Stats
DNA / RNA

Analyze PCR primer properties: melting temperature (3 methods), GC content, self-annealing, hairpin formation, and PCR suitability.

qPCR Quantitation
Methods

Generate standard curves and quantify unknown samples from qPCR data. Calculates R², PCR efficiency, and back-calculates concentrations.

OD260 Concentration
DNA

Calculate nucleic acid concentration from OD260 measurements using Beer-Lambert law. Supports ssDNA, dsDNA, and ssRNA.

RNA Mass Moles Converter
RNA

Convert between mass and moles for ssRNA and dsRNA sequences. Calculates molecular weight, copy number, and moles of ends.

DNA Mass Moles Converter
DNA

Convert between mass and moles for ssDNA and dsDNA sequences. Uses exact nucleotide weights when sequence is provided.

Dilution Calculator
Methods

Calculate dilution volumes using the C₁V₁=C₂V₂ formula. Instantly find how much stock solution and solvent you need.